MBL 株式会社医学生物学研究所 臨床検査薬

このサイトは、医療従事者の方を対象に情報を提供しています。

間接蛍光抗体法による抗核抗体写真集

参考文献

<総説>
  •  Bradwell AR, Stokes RP, Johnson GD. Atlas of HEp-2 patterns.THE BINDING SITE, 1995
  •  Krapf AR, et al. Atlas of Immunofluorescent Autoantibodies. Urban & Schwarzenberg, 1996
  •  三森経世. 抗核抗体研究の進歩-自己抗体が認識する核および細胞質蛋白の構造と機能-.リウマチ 32(4) : 366-78, 1992
  •  三森経世. 新しい自己抗体とその対応抗原.最新内科学体系プログレス4 , p146-57. 中山書店, 東京, 1997

  • <各自己抗体>
  •  宮脇昌二, 浅沼浩子. 間接蛍光抗体法による抗核抗体染色型の再検討. 辺縁型(peripheral pattern)に関する問題点.リウマチ 36(4) : 644-50, 1996
  • Herrera-Diosdado R, Avalos-Diaz E, Herrera-Esparza R. Cross-reactivity of anti-nDNA antibodies with nuclear envelope proteins. Isolation of a cDNA encoding the 70 kDa annular protein recognized by autoantibodies from patients with systemic lupus erythematosus. Rev Rhum Engl Ed 64, 82-8, 1997 [PMID:9085441]
  •  大西勝憲, 小池隆夫. SLEにおける抗ヌクレオソーム抗体の臨床的意義--ループス腎炎との関連.医学のあゆみ 170(2): 156-7, 1994
  • 水島昇 他. 抗ヒストン‐DNA複合体抗体陽性,IgG抗dsDNA抗体陰性のループス腎炎の2例.臨床病理 44(6) : 585-9, 1996
  •  杉本正毅. 各種膠原病患者における亜分画別抗ヒストン抗体.日本臨床免疫学会会誌 16(5) : 347-54, 1993
  •  三森経世, 諏訪昭. Ku抗原.炎症と免疫 5(3) : 291-8, 1997
  • Wang J, et al. Human autoantibodies stabilize the quaternary structure of Ku antigen. Arthritis Rheum. 40, 1344-53, 1997 [PMID:9214436]
  •  鏑木淳一. 強皮症と自己抗体.MBL自己免疫レポート No.18, p1-13, MBL, 名古屋, 1997
  •  諸井泰興. 抗セントロメア抗体の検出法と臨床的意義.MBL自己免疫レポート No.7,p1-8, MBL, 名古屋, 1990
  • 岡崎恒子. セントロメアの構造. 蛋白質核酸酵素 41(15) : 2230-9, 1996
  •  東條毅 他. 低分子核内U-RNP抗体群.日本臨床 46(4) : 784-9, 1988
  • Van Venrooij WJ, Sillekens PT. Small nuclear RNA associated proteins: autoantigens in connective tissue diseases. Clin Exp Rheum. 7, 635-45, 1989 [PMID:2692895]
  •  Brahms H, et al. A major, novel systemic lupus erythematosus autoantibody class recognizes the E, F, and G Sm snRNP proteins as an E-F-G complex but not in their denatured states. Arthritis Rheum. 40, 672-82, 1997 [PMID:9125249]
  •  Fritzler MJ, Ali R, Tan EM. Antibodies from patients with mixed connective tissue disease react with heterogeneous nuclear ribonucleoprotein or ribonucleic acid (hnRNP/RNA) of the nuclear matrix. J Immunol. 132, 1216-22, 1984 [PMID:6198384]
  • Steiner G, Skriner K, Smolen JS. Autoantibodies to the A/B proteins of the heterogeneous nuclear ribonucleoprotein complex: novel tools for the diagnosis of rheumatic diseases. Int Arch Allergy Immunol. 111, 314-9, 1996 [PMID:8957102]
  • Montecucco C, et al. Identification of autoantibodies to the I protein of the heterogeneous nuclear ribonucleoprotein complex in patients with systemic sclerosis. Arthritis Rheum. 39, 1669-76, 1996 [PMID:8843857]
  • Stanek D, et al. Heterogenous nuclear RNP C1 and C2 core proteins are targets for an autoantibody found in the serum of a patient with systemic sclerosis and psoriatic arthritis. Arthritis Rheum 40, 2172-7, 1997 [PMID:9416854]
  •  伊藤保彦. 新生児ループスの発症機序とRo52.リウマチ 36(4) : 884-90, 1996
  •  西川武二 他. 免疫異常を伴う再発性紅斑:抗SS-B再発性紅斑.日本皮膚科学会雑誌 98(8) : 825-34, 1988
  •  Andrade LE, et al. Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin. J Exp Med. 173, 1407-19, 1991 [PMID:2033369]
  • Andrade LE, Tan EM, Chan EK. Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation. Proc Natl Acad Sci USA. 90, 1947-51, 1993 [PMID:8446613]
  •  Szostecki C, et al. Autoimmune sera recognize a 100 kD nuclear protein antigen (sp-100). Clin exp Immunol 68, 108-16, 1987 [PMID:3308206]
  • Andre C, et al. The PML and PML/RAR alpha domains: from autoimmunity to molecular oncology and from retinoic acid to arsenic. Exp Cell Res. 229, 253-60, 1996 [PMID:8986606]
  • Zuber M, Heyden TS, Lajous-Petter AM. A human autoantibody recognizing nuclear matrix-associated nuclear protein localized in dot structures. Biol Cell. 85, 77-86, 1995 [PMID:8882521]
  •  桑名正隆 他. 全身性強皮症で免疫沈降法により同定される抗核小体抗体の臨床的意義. リウマチ 32 (1): 39-46, 1992
  •  今井明彦. 肝疾患・肝癌と自己抗体.MBL自己免疫レポート No.15, p1-16, MBL, 名古屋, 1995
  • Fujii T, Mimori T, Akizuki M. Detection of autoantibodies to nucleolar transcription factor NOR90/hUBF in sera of patients with rheumatic diseases, by recombinant autoantigen-based assays. Arthritis Rheum. 39, 1313-8, 1996 [PMID:8702439]
  •  Arnett FC, Reveille JD, Valdez BC. Autoantibodies to a nucleolar RNA helicase protein in patients with connective tissue diseases. Arthritis Rheum. 40, 1487-92, 1997 [PMID:9259430]
  • Valdez BC, et al. A nucleolar RNA helicase recognized by autoimmune antibodies from a patient with watermelon stomach disease.Nucleic Acids Res. 24, 1220-4, 1996 [PMID:8614622]
  •  Imai H, et al. Nucleolar antigens and autoantibodies in hepatocellular carcinoma and other malignancies. Am J Pathol. 140, 859-70, 1992 [PMID:1314027]
  •  Ochs RL, et al. cDNA cloning and characterization of a novel nucleolar protein. Mol Biol Cell. 7, 1015-24, 1996 [PMID:8862517]
  •  高崎芳成. 抗PCNA抗体. 臨床検査 41(5) : 529-34, 1997
  • 橋本博史 他. 抗Ki抗体のPCNA複合体に対する反応性の検討. 厚生省自己免疫疾患調査研究班平成7年度研究報告書, p113-5, 1996
  • Takeuchi K, et al. Autoantibodies recognizing proteins copurified with PCNA in patients with connective tissue diseases. Mol Biol Rep. 23, 243-6, 1996 [PMID:9112235]
  •  岡野哲郎, 三森経世, 秋月正史. 抗Na抗体:細胞周期関連抗原を認識する自己抗体. 日本臨床免疫学会誌 14(3) : 258-66, 1991
  • 岡野哲郎, 三森経世. 抗Na抗体-細胞周期関連抗原を認識する自己抗体-. 臨床病理 45(5) : 481-7, 1994
  •  Liao H, et al. CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis. J Cell Biol. 130, 507-18, 1995 [PMID:7542657]
  • Rattner JB, et al. High frequency of neoplasia in patients with autoantibodies to centromere protein CENP-F. Clin Invest Med. 20, 308-19, 1997 [PMID:9336656]
  •  Fritzler MJ, et al. An antigen in metaphase chromatin and the midbody of mammalian cells bind to scleroderma sera. J Rheumatol. 14, 291-4, 1987 [PMID:3598998]
  •  Humbel RL. Detection of antinuclear antibodies by immunofluorescence. in Man Biol Mark A2: 1-16, Kluwer Academic Pubs. Netherlands, 1994
  •  玉井克之. DNA複製装置と増殖関連抗原. 病理と臨床 9(7) : 855-61, 1991
  •  相澤良夫, 戸田剛大郎. 原発性胆汁性肝硬変(PBC)に出現する抗核抗体(ANA)の多様性とその臨床的意義. 医学のあゆみ 172(7) : 423-6, 1995
  • Konstantinov K, et al. Integral membrane proteins associated with the nuclear lamina are novel autoimmune antigens of the nuclear envelope. Clin Immunol Immunopathol. 74, 89-99, 1995 [PMID:7527749]
  •  von Mikecz A, et al. High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis Rheum. 40, 295-305, 1997 [PMID:9041942]
  • Hill C, et al. Clinical associations of anti-lamin autoantibodies. Aust NZ J Med. 26, 162-6, 1996 [PMID:8744613]
  • Brito J, et al. Autoantibodies to human nuclear lamin B2 protein. Epitope specificity in different autoimmune diseases. J Immunol. 153, 2268-77, 1994 [PMID:7519647]
  •  Courvalin JC, Worman HJ. Nuclear envelope protein autoantibodies in primary biliary cirrhosis. Semin Liver Dis. 17, 79-90, 1997 [PMID:9089913]
  • Wesierska-Gadek J, et al. Autoantibodies from patients with primary biliary cirrhosis preferentially react with the amino-terminal domain of nuclear pore complex glycoprotein gp210. J Exp Med. 182, 1159-62, 1995 [PMID:7561689]
  •  森藤隆夫, 黒田聖仁. 抗ミトコンドリア抗体(2).MBL自己免疫レポート No.9, p1-9, MBL, 名古屋, 1990
  • Nishio A, et al. Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis. Hepatology. 25, 1085-9, 1997 [PMID:9141421]
  •  Isshi K, Hirohata S. Association of anti-ribosomal P protein antibodies with neuropsychiatric systemic lupus erythematosus. Arthritis Rheum. 39, 1483-90, 1996 [PMID:8814059]
  • Fujimoto M, et al. Anti-ribosomal P protein antibodies in a Japanese patient with systemic sclerosis. J Dermatol. 23, 33-6, 1996 [PMID:8720255]
  • 内海利男. リボソーム自己抗原部位の構造と機能. 自己抗体と自己免疫'97 (第4回自己抗体と自己免疫シンポジウム講演録集), p13-19, MBL, 名古屋, 1997
  •  Vazquez-Abad D, Carson JH, Rothfield N. Localization of histidyl-tRNA synthetase (Jo-1) in human laryngeal epithelial carcinoma cell line (HEp-2 cells). Cell Tissue Res. 286, 487-91, 1996 [PMID:8929351]
  •  Friedman AW, Targoff IN, Arnett FC. Interstitial lung disease with autoantibodies against aminoacyl-tRNA synthetases in the absence of clinically apparent myositis. Semin Arthritis Rheum. 26, 459-67, 1996 [PMID:8870113]
  •  Hirakata M, et al. Autoantibodies to small nuclear and cytoplasmic ribonucleoproteins in Japanese patients with inflammatory muscle disease. Arthritis Rheum. 35, 449-56, 1992 [PMID:1567494]
  •  Griffith KJ, et al. Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjogren's syndrome. Arthritis Rheum. 40, 1693-702, 1997 [PMID:9324025]
  • Ikonen E, et al. Myosin II is associated with golgi membranes: identification of p200 as nonmuscle myosin II on golgi-derived vesicles. J Cell Sci. 110, 2155-64, 1997 [PMID:9378765]
  •  Howard MK, Gull K, Miles MA. Antibodies to tubulin in patients with parasitic infections. Clin Exp Immunol. 68, 78-85, 1987 [PMID:3115642]
  • Connolly AM, Pestronk A. Anti-tubulin autoantibodies in acquired demyelinating polyneuropathies. J Infect Dis. 176 Suppl 2, S157-9, 1997 [PMID:9396702]
  •  Andrade LE, et al. Two major autoantigen-antibody systems of the mitotic spindle apparatus. Arthritis Rheum. 39, 1643-53, 1996 [PMID:8843854]
  • Whitehead CM, et al. The spindle kinesin-like protein HsEg5 is an autoantigen in systemic lupus erythematosus. Arthritis Rheum. 39, 1635-42, 1996 [PMID:8843853]
  •  Rattner JB, et al. Autoantibodies to the centrosome (centriole) react with determinants present in the glycolytic enzyme enolase. J Immunol. 46, 2341-4, 1991 [PMID:1706394]
  • Sato S, et al. Antibodies to centromere and centriole in scleroderma spectrum disorders. Dermatology. 189, 23-6, 1994 [PMID:8003781]
  •  Fusconi M, et al. Anti-actin antibodies: a new test for an old problem. J Immunol Methods. 130, 1-8, 1990 [PMID:2193058]
  • Czaja AJ, et al. requency and significance of antibodies to actin in type 1 autoimmune hepatitis. Hepatology. 24, 1068-73, 1996 [PMID:8903377]
  •  Cordonnier C, et al. Diagnostic value of anti-RA33 antibody, antikeratin antibody, antiperinuclear factor and antinuclear antibody in early rheumatoid arthritis: comparison with rheumatoid factor. Br J Rheumatol. 35, 620-4, 1996 [PMID:8670593]
  •  近藤啓文, 鈴木貴博. 抗ビメンチン抗体の検出法と臨床的意義.MBL自己免疫レポート No.5, p1-8, MBL, 名古屋, 1989
  •  Wiik AS, et al. Antinuclear antibodies: a contemporary nomenclature using HEp-2 cells. J Autoimmun. 35, 276-90, 2010 [PMID:20650611]
  •  Nakashima R, et al. The multicenter study of a new assay for simultaneous detection of multiple anti-aminoacyl-tRNA synthetases in myositis and interstitial pneumonia. PLoS One. 9, e85062, 2014 [PMID: 24454792]
  • Hozumi H, et al. Prognostic significance of anti-aminoacyl-tRNA synthetase antibodies in polymyositis/dermatomyositis-associated interstitial lung disease: a retrospective case control study. PLoS One. 10, e0120313, 2015 [PMID: 25789468]
  •  Covini G, et al. Cytoplasmic rods and rings autoantibodies developed during pegylated interferon and ribavirin therapy in patients with chronic hepatitis C. Antivir Ther. 17, 805-11, 2012 [PMID: 22293655]
  • Carcamo WC, et al. Induction of Cytoplasmic Rods and Rings Structures by Inhibition of the CTP and GTP Synthetic Pathway in Mammalian Cells. PLoS One. 6, e29690, 2011 [PMID: 22220215]
  • Seelig HP, et al. Autoantibodies against Inosine-5’-Monophosphate Dehydrogenase2 – Characteristics and Prevalence in Patients with HCV-Infection. Clin Lab. 57, 753-65, 2011 [PMID: 22029192]
  • Liu JL. The enigmatic cytoophidium: compartmentation of CTP synthase via filament formation. Bioessays. 33, 159-64, 2011 [PMID: 21254152]
  • Alessandra Dellavance, et al. Third Brazilian Consensus for autoantibodies screening in HEp-2 cells (ANA). Recommendations for standardization of autoantibodies screening trial in HEp-2 cells,quality control and clinical associations. Rev Bras Reumatol. 49, 89-109, 2009